• Medicina clinica · Oct 2023

    Heart rate disorders in patients with Tako-tsubo syndrome.

    • Oscar Vedia, Manuel Almendro-Delia, Javier López-País, Alberto Pérez-Castellanos, Aitor Uribarri, Albert Duran-Cambra, Agustín Martín-García, Iván J Núñez-Gil, and en representación del Grupo de Trabajo.
    • Instituto Cardiovascular, Hospital Clínico San Carlos, Madrid, España; Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, España. Electronic address: oscarvediacruz@gmail.com.
    • Med Clin (Barc). 2023 Oct 27; 161 (8): 330337330-337.

    ObjectivesThis study sought to evaluate the incidence, prognosis and treatment of heart rhythm disorders (HRD) in Tako-tsubo syndrome (TTS).BackgroundTTS is associated with HRD. The HRD prognostic value is not well characterized in TTS yet.MethodsThe HRD of patients included in the National Registry of Tako-tsubo syndrome, admitted between 2002 and 2018 and coming from 38 hospitals throughout the country, was analyzed. We analyzed any heart rhythm disorder in patients presented before admission, at admission and in long-term follow-up.ResultsAll types of HRD were described in 259 (23.5%) cases, from a cohort of 1,097 consecutive patients with TTS. HRD was more associated with diabetes mellitus, smoking, hyperuricemia, sleep apnea, anemia with a worse LVEF on admission. The most frequent HRD was a new onset of atrial fibrillation. During hospitalization, patients with HRD showed more complications such as shock on admission, major bleeding, acute renal failure, and combined infections. At follow-up, they presented higher mortality and more major adverse cardiac events, but with a non-significant correlation.ConclusionsThe incidence of HRD in patients with TTS is not infrequent. TTS, when associated with HRD, presents more complications and a worse prognosis both in hospital and in the long term.Copyright © 2023 Elsevier España, S.L.U. All rights reserved.

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