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J Neurosurg Anesthesiol · Oct 2023
ReviewCerebral Autoregulation-guided Management of Adult and Pediatric Traumatic Brain Injury.
- Abhijit V Lele and Monica S Vavilala.
- Department of Anesthesiology and Pain Medicine.
- J Neurosurg Anesthesiol. 2023 Oct 1; 35 (4): 354360354-360.
AbstractCerebral autoregulation (CA) plays a vital role in maintaining cerebral blood flow in response to changes in systemic blood pressure. Impairment of CA following traumatic brain injury (TBI) may exacerbate the injury, potentially impacting patient outcomes. This focused review addresses 4 key questions regarding the measurement, natural history of CA after TBI, and potential clinical implications of CA status and CA-guided management in adults and children with TBI. We examine the feasibility and safety of CA assessment, its association with clinical outcomes, and the potential for reversing deranged CA following TBI. Finally, we discuss how the knowledge of CA status may affect TBI management and outcomes.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
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