• Ann. Intern. Med. · Aug 2023

    Comment Randomized Controlled Trial Multicenter Study

    In uncontrolled T2DM treated with a basal-bolus insulin regimen, weekly icodec was noninferior to daily glargine for HbA1c at 26 wk.

    • Heiba Belal and Gunjan Y Gandhi.
    • University of Florida, Jacksonville, Florida, USA (H.B., G.Y.M.).
    • Ann. Intern. Med. 2023 Aug 1; 176 (8): JC94JC94.

    AbstractMathieu C, Ásbjörnsdóttir B, Bajaj HS, et al. Switching to once-weekly insulin icodec versus once-daily insulin glargine U100 in individuals with basal-bolus insulin-treated type 2 diabetes (ONWARDS 4): a phase 3a, randomised, open-label, multicentre, treat-to-target, non-inferiority trial. Lancet. 2023;401:1929-1940. 37156252.

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