• J Janota, J Simak, Z Stranak, T Matthews, T Clarke, and D Corcoran.
• Department of Paediatrics, The Rotunda Hospital, Parnell Square, Dublin 1, Ireland. janjanota@yahoo.com
• Ir J Med Sci. 2008 Mar 1;177(1):11-7.

BackgroundThe neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality.AimTo test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants.MethodsThe system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life.ResultsA NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality.ConclusionsThe NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.

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