• David Pasquier, Luc Bidaut, Daniela Elena Oprea-Lager, Nandita M deSouza, David Krug, Laurence Collette, Wolfgang Kunz, Yazid Belkacemi, Maria Grazia Bau, Caroline Caramella, Lioe-Fee De Geus-Oei, Alex De Caluwé, Christophe Deroose, Olivier Gheysens, Ken Herrmann, Isabelle Kindts, Michalis Kontos, Sherko Kümmel, Barbro Linderholm, Egesta Lopci, Icro Meattini, Ann Smeets, Orit Kaidar-Person, Philip Poortmans, Pelagia Tsoutsou, Nawale Hajjaji, Nicola Russell, Elżbieta Senkus, Jean-Noël Talbot, Lale Umutlu, Vincent Vandecaveye, Joost J C Verhoeff, Willemien Menke-van der Houven van Oordt, Helle D Zacho, Fatima Cardoso, Laure Fournier, Frederieke Van Duijnhoven, and Frédéric E Lecouvet.
• Academic Department of Radiation Oncology, Centre Oscar Lambret, Lille, France; University of Lille and CNRS, Centrale Lille, UMR 9189-CRIStAL, Lille, France. Electronic address: d-pasquier@o-lambret.fr.
• Lancet Oncol. 2023 Aug 1; 24 (8): e331e343e331-e343.

AbstractBreast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic disease and clinical trials of oligometastatic breast cancer. After an exhaustive review of the literature covering all aspects of oligometastatic breast cancer, 35 experts from the European Organisation for Research and Treatment of Cancer Imaging and Breast Cancer Groups elaborated a Delphi questionnaire aimed at offering consensus recommendations, including oligometastatic breast cancer definition, optimal diagnostic pathways, and clinical trials required to evaluate the effect of diagnostic imaging strategies and metastasis-directed therapies. The main recommendations are the introduction of modern imaging methods in metastatic screening for an earlier diagnosis of oligometastatic breast cancer and the development of prospective trials also considering the histological and molecular complexity of breast cancer. Strategies for the randomisation of imaging methods and therapeutic approaches in different subsets of patients are also addressed.Copyright © 2023 Elsevier Ltd. All rights reserved.

16 keywords...

hide…