• Internal medicine · Apr 2024

    Hodgkin Lymphoma-related Inflammatory Modification-displayed Castleman Disease-like Histological Features and Positron Emission Tomography/Computed Tomography Usefulness for the Differential Diagnosis: A Case Report.

    • Hirofumi Yamauchi, Mamiko Momoki, Yutaro Kamiyama, Tadahiro Gunji, Hiroki Yokoyama, Takeshi Saito, David Boutboul, Eric Oksenhendler, and Shingo Yano.
    • Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan.
    • Intern. Med. 2024 Apr 1; 63 (7): 993998993-998.

    AbstractHodgkin lymphoma (HL) and idiopathic multicentric Castleman disease (iMCD) are markedly different conditions. However, in some cases, histological similarities caused by elevated cytokines, including interleukin-6, can lead to a misdiagnosis of HL as Castleman disease (CD). We herein report a patient with HL who had been diagnosed with CD by an expert panel and for whom an additional biopsy was useful for determining the correct diagnosis. Furthermore, we analyzed the positron emission tomography/computed tomography findings at the diagnosis and found that the maximum standardized uptake value was useful for distinguishing HL from iMCD.

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