• Internal medicine · Jan 2023

    Case Reports

    Adult-onset Still's Disease Diagnosed during Puerperium with Liver Dysfunction in Pregnancy and Liver Failure of the Infant.

    • Kenjo Tanaka, Takeharu Asano, Eri Watanabe, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takaya Miura, Yuko Takahashi, Rumiko Tsuboi, Takehiro Ishii, Haruka Otake, Shuhei Yoshikawa, Takeshi Uehara, Masanari Sekine, Satohiro Matsumoto, Shinichi Asabe, Hiroyuki Miyatani, and Hirosato Mashima.
    • Department of Gastroenterology, Saitama Medical Center, Jichi Medical University, Japan.
    • Intern. Med. 2023 Jan 1; 62 (16): 234923542349-2354.

    AbstractMost cases of liver dysfunction in pregnancy are pregnancy-related, but the onset of systemic autoimmune diseases is also differentiated. A 24-year-old woman presented with liver dysfunction at 28 weeks' gestation with suspected autoimmune hepatitis and started taking ursodeoxycholic acid. She gave birth prematurely at 35 weeks' gestation, and the infant presented with pancytopenia and liver failure but survived because of liver transplantation. Since the patient had major symptoms during the puerperium, she was diagnosed with adult-onset Still's disease. When encountering a patient with liver dysfunction during pregnancy, we should also consider the onset of autoimmune diseases.

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