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Review Case Reports
Distal Chronic Inflammatory Demyelinating Polyneuropathy Following COVID-19 Vaccination in a Patient with Solitary Plasmacytoma: A Case Report and Literature Review.
- Takafumi Kubota, Tomomi Shijo, Kensho Ikeda, Yoshihiko Mitobe, Shu Umezawa, Tatsuro Misu, Takafumi Hasegawa, and Masashi Aoki.
- Department of Neurology, Tohoku University Graduate School of Medicine, Japan.
- Intern. Med. 2023 Jan 1; 62 (16): 241924252419-2425.
AbstractWe herein report a rare case of distal chronic inflammatory demyelinating polyneuropathy (CIDP) following coronavirus disease 2019 (COVID-19) vaccination. A 39-year-old woman with a solitary plasmacytoma developed general weakness 7 days after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine, which had progressed for 3 months. A neurological examination revealed limb weakness with areflexia. Serological tests identified the presence of IgG antibodies against anti-GM1 and anti-GM2 gangliosides. Comprehensive evaluations met the criteria of distal CIDP. Intravenous immunoglobulin, intravenous methylprednisolone, oral prednisolone, and plasma exchange were administered, and she gradually improved. Physicians should be aware of CIDP as a rare complication of COVID-19 vaccination.
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