• Juan Gao, Han-Qiao Liu, Yan Wang, Ya-Li Shang, and Fang Hu.
• Gynecology Department, Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang.
• Medicine (Baltimore). 2019 Mar 1; 98 (10): e14772e14772.

BackgroundThis systematic review will be proposed for investigating the effects of psychological care (PC) in patients with endometriosis.MethodsWe will search the following 7 electronic databases from inception to the present: MEDLINE, EMBASE, SinoMed, Web of Science, Cochrane Library, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. We will include randomized controlled trials for evaluating the effects of PC in patients with endometriosis. Cochrane risk of bias tool will be used to evaluate the methodological quality for each included study. Two authors will independently carry out the study selection, data extraction, and methodological quality evaluation. Any disagreements will be solved by a third author through discussion.ResultsThis proposed systematic review will use high-quality evidence-based medicine to evaluate the efficacy and safety of PC for endometriosis. The primary outcomes include depression and anxiety. The secondary outcomes consist of pain intensity, health-related quality of life, and adverse events.ConclusionThe findings of this study will provide convincing evidence to determine whether PC therapy is an effective and safe intervention for patients with endometriosis.Prospero Registration NumberPROSPERO CRD42019123292.

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