• Roxana A Damilano, Natalia L Monteserin, Carolina Fux Otta, Jorge H Mukdsi, Paula Mereshian, Marta Andrada, and Grupo Neuroendocrinología, Sociedad de Endocrinología y Metabolismo de Córdoba (SEMCO).
• Servicio de Endocrinología, Sanatorio Allende, Córdoba, Argentina. E-mail: roxanadamilano@hotmail.com.
• Medicina (B Aires). 2023 Jan 1; 83 (4): 514521514-521.

IntroductionPituitary incidentalomas (PIs) are lesions found incidentally in the pituitary on imaging performed for reasons unrelated to pituitary disease.MethodsA cross-sectional, retrospective and descriptive study was carried out with the aim of analyzing the clinical and evolutionary characteristics of a population of patients with PIs in the city of Córdoba.ResultsA total of 67 patients were included, 67% female, with a median age at diagnosis of 44 years. Among the reasons that led to requesting the first image, chronic or recurrent headache was the most prevalent (34%). The median tumor size was 12 mm. Fifty-eight percent were macroincidentalomas. Men had significantly larger lesions (p = 0.04). At diagnosis, including both sexes, 30% showed extrasellar extension and 45% invasion of the cavernous sinuses. Neuro-ophthalmological compromise was detected in 21%. A positive correlation was found between age at diagnosis and tumor size (r= +0.31, p = 0.001). Ninety-one percent were non-functioning tumors and at presentation, 21% of patients had one or more hormonal deficiencies. Of the total, 26% required surgery. Most of those who continued without treatment showed no change in tumor size at the end of follow-up (median 42 months).ConclusionWe highlight the high frequency of macroincidentalomas in our series, with visual field defects and hypopituitarism being frequent at diagnosis. Although most non-operated PIs remained stable, there was a high frequency of clinically significant lesions.

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