• Internal medicine · Apr 2024

    Review Case Reports

    A Rare Case of Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Leading to Hemodialysis and Multiple Infections: A Case Report and Literature Review.

    • Yohei Iwashige, Shinya Yamamoto, Kaoru Ohue, Hisashi Sugimoto, Hiroyuki Yabumoto, Ryo Kamimatsuse, Hisashi Kamido, Ryota Akagi, Minami Matsumoto, Kanae Yamamoto-Nonaka, Sachiko Minamiguchi, and Motoko Yanagita.
    • Department of Nephrology, Kyoto University, Japan.
    • Intern. Med. 2024 Apr 15; 63 (8): 113111381131-1138.

    AbstractDrug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe drug eruption that causes multiple organ damage. The renal impairment in these patients usually improves with immunosuppressants, but subsequent infections often develop. We herein report a rare case of DRESS syndrome leading to hemodialysis and multiple infections with Pneumocystis pneumonia, cytomegalovirus and Aspergillus despite the administration of low-dose prednisolone. We also present a literature review of cases requiring dialysis after DRESS syndrome. In patients with chronic kidney disease, it is important to be alert for not only the development of DRESS syndrome but also subsequent infections.

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