• Medicine · Mar 2019

    Meta Analysis

    The efficacy and safety of opening-wedge high tibial osteotomy in treating unicompartmental knee osteoarthritis: Protocol for a systematic review and meta-analysis.

    • Si-Cong Huang, Yu-Fang Chen, Xue-Dong Liu, Yan-Hong Han, and Yi-Qun Li.
    • The Second People's Hospital of Foshan (Affiliated Foshan Hospital of Southern Medical University), Foshan.
    • Medicine (Baltimore). 2019 Mar 1; 98 (12): e14927e14927.

    BackgroundHigh tibial osteotomy (HTO) is an effective surgical technique that can stop or inhibit the progression of unicompartmental knee osteoarthritis (KOA) to avoid or postpone the need for knee arthroplasty in patients. Whether opening-wedge high tibial osteotomy (OWHTO) is superior to closing-wedge high tibial osteotomy (CWHTO) in treating unicompartmental KOA remains controversial.MethodsDatabases (Cochrane Library, EMBASE, and PubMed) were searched from their establishment to July 1, 2018 for randomized controlled trials comparing the application of OWHTO to CWHTO in patients with unicompartmental KOA. The methodological quality of each included study was assessed according to the Cochrane Handbook for Systematic Reviews of Interventions guideline. Review Manager 5.3.5 software (Cochrane Collaboration, Oxford, UK) was used to synthesize the final results.ResultsThe results will provide useful information about the effectiveness and safety of OWHTO in patients with unicompartmental KOA.ConclusionThe findings of the study will be published in a peer-reviewed journal.Prospero Registration NumberCRD4201811805.

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