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- Bei Pan, Hongli Li, Yunhua Wang, Min Sun, Hui Cai, and Jiancheng Wang.
- Gansu Provincial Hospital, Lanzhou.
- Medicine (Baltimore). 2019 Aug 1; 98 (35): e16955e16955.
BackgroundFrailty has become one of the biggest challenges in facilitating healthy aging. Our study aims to investigate the association between physical activity and the risk of frailty, meanwhile, conduct a dose-response to observe the relationship between physical activity volume and frailty.MethodWe will systematically search six databases to identify cohort studies assessing the association between physical activity and risk of frailty. Risk of bias of individual study will be assessed using the Newcastle-Ottawa Scale. Data will be analyzed by using STATA V.12.0.ResultsThe results of this study will be published in a peer-reviewed journal.ConclusionWe will first investigate whether specific-physical activity reduce the risk to onset frailty in healthy older adults. However, predictable heterogeneity may exist in our study because of the inconsistent definitions of frailty.
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