• Medicine · Dec 2019

    Meta Analysis

    Clinical efficacy and safety of Shenqi Fuzheng injection for the treatment of chronic heart failure: Protocol for a meta-analysis and systematic review.

    • Chuan Wang, Dongfeng Yao, Pan Zhang, Xiaowei Xie, Bin Wang, Jiping Liu, and Zhen Zhang.
    • Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang.
    • Medicine (Baltimore). 2019 Dec 1; 98 (52): e18556e18556.

    BackgroundChronic heart failure (CHF) is one of the most serious cardiovascular diseases. Shenqi Fuzheng injection (SQFZI), as a Chinese herbal injection, is usually used for the treatment of CHF. However, the clinical evidence of SQFZI for the treatment of CHF is unclear.MethodsTwo researchers will dependently search literatures of SQFZI for CHF from Chinese National Knowledge Infrastructure database, VIP database, Chinese Biological and Medicine database, Wangfang database, MEDLINE, EMBASE, Cochrane Library and Web of Science. These inclusive data of included studies will be conducted by RevMan 5.3 software.ResultsThis meta-analysis and systematic review will provide a series of outcome measures to verify clinical efficacy and safety of SQFZI for treating CHF, including New York Heart Association (NYHA) function classification, left ventricular ejection fraction, left ventricular end-diastolic dimension, cardiac output, stroke volume, brain natriuretic peptide, N-terminal pro-brain natriuretic peptide, and adverse events.ConclusionsThis meta-analysis and systematic review will provide up-to-date clinical evidence to assess SQFZI treatment efficacy for CHF patients.

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