• Internal medicine · Apr 2024

    Review Case Reports

    Human T-cell Lymphotropic Virus Type-1-associated Bronchioloalveolar Disorder with Non-necrotizing Granulomas: A Case Report and Literature Review.

    • Satomi Kimura, Yukihiro Umeda, Ryoko Egashira, Kazuhiro Tabata, Akifumi Muramoto, Mihoko Morita, Makiko Yamaguchi, Yuko Waseda, Yoshiaki Imamura, Takahiro Yamauchi, and Tamotsu Ishizuka.
    • Division of Respiratory Medicine, University of Fukui Hospital, Japan.
    • Intern. Med. 2024 Apr 15; 63 (8): 114911551149-1155.

    AbstractHuman T-cell lymphotropic virus type-1 (HTLV-1)-associated bronchioloalveolar disorder (HABA) is a pulmonary disorder characterized by lymphocytic infiltration of the peribronchiolar space and interstitium in HTLV-1 carriers and in adult T-cell leukemia/lymphoma (ATLL). We herein report an 85-year-old woman carrying HTLV-1 with HABA who presented with a miliary pattern of micronodules in both lungs on high-resolution computed tomography and a lymphocytic infiltrate with non-necrotizing granulomas on pathology. This rare case of HABA should be differentiated from sarcoidosis, hypersensitivity pneumonitis, or miliary tuberculosis.

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