• Eur Spine J · Nov 2023

    Vertebral bone quality score for opportunistic osteoporosis screening: a correlation and optimal threshold analysis.

    • Emre Özmen, Ozancan Biçer, Emre Meriç, Esra Circi, Alican Barış, and Serdar Yüksel.
    • Orthopedics and Traumatology, Istanbul Physical Therapy and Rehabilitation Training and Research Hospital, Adnan Kahveci Blv. No: 145, 34186, Bahçelievler, Istanbul, Turkey. emreozmen@istanbul.edu.tr.
    • Eur Spine J. 2023 Nov 1; 32 (11): 390639113906-3911.

    PurposeThis study investigated the vertebral bone quality (VBQ) score as a potential tool for opportunistic osteoporosis screening and its correlation with dual-energy X-ray absorptiometry (DXA) values.MethodsIn a single-center retrospective cohort of 130 patients, VBQ and DXA measures were compared using various statistical analyses. The optimal VBQ threshold for predicting osteoporosis was determined using receiver operating characteristic (ROC) analysis.ResultsVBQ exhibited a significant negative association with DXA values, suggesting that higher VBQ scores are indicative of lower bone density. Age and VBQ were significant predictors of osteoporosis, with both increasing the log-odds of the condition. An optimal VBQ threshold of 2.7 was determined, demonstrating fair discriminatory power and high negative predictive value.ConclusionThe study highlighted the potential of VBQ as a diagnostic tool for osteoporosis with high intra- and inter-observer reliability. The optimal VBQ threshold of 2.7 can aid in ruling out osteoporosis and identifying individuals for further evaluation.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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