• Kareem El Naamani, Adam Hunt, Paarth Jain, Charles L Lawall, Clifford J Yudkoff, Omar El Fadel, Marc Ghanem, Panagiotis Mastorakos, Arbaz A Momin, Abdulaziz Alhussein, Reyoof Alhussein, Elias Atallah, Rawad Abbas, Rida Zakar, Stavropoula I Tjoumakaris, M Reid Gooch, Nabeel A Herial, Hekmat Zarzour, Richard F Schmidt, Robert H Rosenwasser, and Pascal M Jabbour.
• Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia , Pennsylvania , USA.
• Neurosurgery. 2023 Dec 1; 93 (6): 141514241415-1424.

Background And ObjectivesNumerous studies of various populations and diseases have shown that unplanned 30-day readmission rates are positively correlated with increased morbidity and all-cause mortality. In this study, we aim to provide the rate and predictors of 30-day readmission in patients undergoing treatment for unruptured intracranial aneurysms.MethodsThis is a retrospective study of 525 patients presenting for aneurysm treatment between 2017 and 2022. All patients who were admitted and underwent a successful treatment of their unruptured intracerebral aneurysms were included in the study. The primary outcome was the rate and predictors of 30-day readmission.ResultsThe rate of 30-day readmission was 6.3%, and the mean duration to readmission was 7.8 days ± 6.9. On univariate analysis, factors associated with 30-day readmission were antiplatelet use on admission (odds ratio [OR]: 0.4, P = .009), peri-procedural rupture (OR: 15.8, P = .007), surgical treatment of aneurysms (OR: 2.2, P = .035), disposition to rehabilitation (OR: 9.5, P < .001), and increasing length of stay (OR: 1.1, P = .0008). On multivariate analysis, antiplatelet use on admission was inversely correlated with readmission (OR: 0.4, P = .045), whereas peri-procedural rupture (OR: 9.5, P = .04) and discharge to rehabilitation (OR: 4.5, P = .029) were independent predictors of 30-day readmission.ConclusionIn our study, risk factors for 30-day readmission were aneurysm rupture during the hospital stay and disposition to rehabilitation, whereas the use of antiplatelet on admission was inversely correlated with 30-day readmission. Although aneurysm rupture is a nonmodifiable risk factor, more studies are encouraged to focus on the correlation of antiplatelet use and rehabilitation disposition with 30-day readmission rates.Copyright © Congress of Neurological Surgeons 2023. All rights reserved.

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