• Sao Paulo Med J · May 2016

    Frequency of cholecystectomy and associated sociodemographic and clinical risk factors in the ELSA-Brasil study.

    • Kamila Rafaela Alves, Alessandra Carvalho Goulart, Roberto Marini Ladeira, OliveiraIlka Regina Souza deIRMD, PhD. Professor, Department of Radiology, School of Medicine, Universidade de São Paulo (USP), São Paulo, SP, Brazil., and Isabela Martins Benseñor.
    • BSc. Postgraduate Student, Department of Medicine, Education and Health, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
    • Sao Paulo Med J. 2016 May 1; 134 (3): 240250240-50.

    Context And ObjectiveThere are few data in the literature on the frequency of cholecystectomy in Brazil. The frequency of cholecystectomy and associated risk factors were evaluated in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).Design And SettingCross-sectional study using baseline data on 5061 participants in São Paulo.MethodsThe frequency of cholecystectomy and associated risk factors were evaluated over the first two years of follow-up of the study and over the course of life. A multivariate regression analysis was presented: odds ratio (OR) and 95% confidence interval (95% CI).ResultsA total of 4716 individuals (93.2%) with information about cholecystectomy were included. After two years of follow-up, 56 had undergone surgery (1.2%: 1.7% of the women; 0.6% of the men). A total of 188 participants underwent cholecystectomy during their lifetime. The risk factors associated with surgery after the two-year follow-up period were female sex (OR, 2.85; 95% CI, 1.53-5.32), indigenous ethnicity (OR, 2.1; 95% CI, 2.28-15.85) and body mass index (BMI) (OR, 1.10; 95% CI, 1.01-1.19 per 1 kg/m2 increase). The risk factors associated over the lifetime were age (OR, 1.03; 95% CI, 1.02-1.05 per one year increase), diabetes (OR, 1.92; 95% CI, 1.34-2.76) and previous bariatric surgery (OR, 5.37; 95% CI, 1.53-18.82). No association was found with parity or fertile age.ConclusionFemale sex and high BMI remained as associated risk factors while parity and fertile age lost significance. New factors such as bariatric surgery and indigenous ethnicity have gained importance in this country.

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