• Tuyen Van Duong, Te-Chih Wong, Chien-Tien Su, Hsi-Hsien Chen, Tzen-Wen Chen, Tso-Hsiao Chen, Yung-Ho Hsu, Sheng-Jeng Peng, Ko-Lin Kuo, Hsiang-Chung Liu, En-Tsu Lin, and Shwu-Huey Yang.
• School of Nutrition and Health Sciences, Taipei Medical University Department of Nutrition and Health Sciences, Chinese Culture University School of Public Health, Taipei Medical University Department of Family Medicine Department of Nephrology, Taipei Medical University Hospital School of Medicine, Taipei Medical University Department of Nephrology, Taipei Medical University-Wan Fang Hospital Division of Nephrology, Department of Internal Medicine, Taipei Medical University Shuang Ho Hospital, Taipei Medical University Division of Nephrology, Cathay General Hospital Division of Nephrology, Taipei Tzu-Chi Hospital, Taipei Department of Nephrology, Wei Gong Memorial Hospital, Miaoli Department of Nephrology, Lotung Poh-Ai Hospital, Yilan Nutrition Research Center, Taipei Medical University Hospital Research Center of Geriatric Nutrition, Taipei Medical University, Taipei, Taiwan.
• Medicine (Baltimore). 2018 Jun 1; 97 (26): e11306e11306.

AbstractThe current study was to examine the association of adequate intake of macronutrients and micronutrients with traditional and nontraditional cardiovascular risk factors in hemodialysis patients.A clinical cross-sectional study was conducted between September 2013 and April 2017 on 492 hemodialysis patients aged 20 years and above, received thrice-weekly hemodialysis treatment for at least 3 months, adequate dialysis quality (equilibrated Kt/V ≥ 1.2 g/kg/d) from 7 hospital-based hemodialysis centers in Taiwan. The dietary intake was evaluated by the 3-day dietary record, and a 24-hour dietary recall. Biochemical parameters were archived from laboratory tests. The cardiovascular disease (CVD) risk factors were defined by the Kidney Disease Outcomes Quality Initiative (K/DOQI) Clinical Practice Guidelines. The adequate dietary intake of macronutrients and micronutrients was recommended by the European Best Practice Guidelines, K/DOQI, and Institute of Medicine guidelines. Logistic regression analysis was used.All hemodialysis patients had CVD risks, the lowest proportion of patients with adequate intake of macronutrients and micronutrients were 8.7% and 1.8%, respectively. The adequate dietary intake associated with lower likelihood of having CVD risks in hemodialysis patient by 47% to 84%, including 39% to 58% lower hypertension, 37% to 50% lower dyslipidemia, 42% to 63% diabetes mellitus, 44% to 84% lower obesity, 58% lower low calcium, 38% lower hyperparathyroidism, 47% to 64% lower hyperhomocysteinemia, and 41% to 67% lower inflammation, 63% to 74% lower hypoalbumin, 73% lower inadequate normalized protein nitrogen appearance.Adequate dietary nutrients intake may reduce the cardiovascular risks factors, in turn, to prevent the cardiovascular morbidity and mortality.

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