• Medicine · Jul 2018

    Case Reports

    Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report.

    • Emanuela Caraffa, Gianluca Russo, Serena Vita, Miriam Lichtner, Anna Paola Massetti, Claudio Maria Mastroianni, Vincenzo Vullo, Maria Rosa Ciardi, and Camilla Ajassa.
    • Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Infectious Diseases Unit, Sapienza University, SM Goretti Hospital, Latina, Italy.
    • Medicine (Baltimore). 2018 Jul 1; 97 (29): e11186e11186.

    RationaleTuberculous meningitis is a highly morbid, often fatal disease.Patient ConcernWe describe a case of an Italian child. DIAGNOSES:: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and paradoxical reaction with brain pseudo-abscesses.InterventionsThe child started readily a specific therapy associated with steroids and thalidomide was introduced few month later.Outcomesthe patient had a favorable outcome without neurologic sequelae.LessonsDespite the prompt specific anti-tubercular and adjuvant corticosteroid therapies, only the addition of thalidomide to the treatment allow to a favorable clinical outcome.

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