• Medicine · Sep 2023

    Review

    A bibliometric analysis of efferocytosis in cardiovascular diseases from 2001 to 2022.

    • Luoxia Hu, Zhengtian Lv, Yangyang Gu, Tiantian Zheng, Youjin Kong, and Wei Mao.
    • Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
    • Medicine (Baltimore). 2023 Sep 29; 102 (39): e34366e34366.

    IntroductionIn recent years, efferocytosis in cardiovascular diseases has become an intense area of research. However, only a few bibliometric analyses have been conducted in this area. In this review, we used CiteSpace 5.7. R2 and VOSviewer 1.6.17 software to perform text mining and knowledge map analysis. This study summarizes the latest progress, development paths, frontier research hotspots, and future research trends in this field.Materials And MethodsStudies on efferocytosis in cardiovascular diseases were downloaded from the Web of Science Core Collection.ResultsIn total, 327 studies published by 506 institutions across 42 countries and regions were identified. The number of studies on efferocytosis in cardiovascular diseases has increased over time. Arteriosclerosis Thrombosis and Vascular Biology published the highest number of articles and was the top co-cited journal. Tabas Ira. was the most prolific researcher and co-cited the most. The most productive countries were the United States and China. Columbia University, Harvard Medical School, and Brigham Women's Hospital were the 3 most productive institutions in the field of research. Keyword Co-occurrence, Clusters, and Burst analyses showed that inflammation, atherosclerosis, macrophages, and phagocytosis appeared with the highest frequency in these studies.ConclusionMultinational cooperation and multidisciplinary intersections are characteristic trends of development in the field, and the immune microenvironment, glycolysis, and lipid metabolism will be the focus of future research.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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