• Am. J. Med. Sci. · Dec 2023

    Review Case Reports

    Organizing pneumonia and COVID-19.

    • Carolina Rodrigues Tonon, Suzana Erico Tanni, Juliana Rocha, Irma Godoy, Bertha Furlan Polegato, Filipe Welson Leal Pereira, Danilo Martins, Robson Aparecido Prudente, Estefania Thome Franco, Fernando Brizola, Bruno Guedes Baldi, and Marina Politi Okoshi.
    • Internal Medicine Department, Botucatu Medical School, Sao Paulo State University, UNESP, Sao Paulo, Brazil.
    • Am. J. Med. Sci. 2023 Dec 1; 366 (6): 458463458-463.

    AbstractOrganizing pneumonia (OP) is an interstitial lung disease, and can be cryptogenic, if no cause is identified, or secondary to several conditions. COVID-19-induced persistent inflammation can be associated with interstitial lung disease. We present a review of literature of OP and COVID-19-induced OP with an illustrative case. A 38-year-old man was admitted with COVID-19 that required mechanical ventilation for 56 days. Initial chest computed tomography (CT) revealed diffuse bilateral ground-glass opacities in the lungs with consolidation areas involving 75 % of the parenchyma. After weaning from MV, the patient still required oxygen supplementation. A new chest CT scan also showed extensive diffuse areas of consolidation and ground-glass opacity. OP was hypothesized and 40 mg/day prednisone initiated and continued for six months with resolution of lung functional and image abnormalities. Organizing pneumonia should be included in the differential diagnosis of COVID-19 patients with respiratory symptoms after partial pulmonary recovery.Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

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