• Marco Foreman, Aashay Patel, Andrew Nguyen, Devon Foster, Adrienne Orriols, and Brandon Lucke-Wold.
• Department of Neurosurgery, University of Florida, Gainesville, Florida, USA. Electronic address: marcoforeman@ufl.edu.
• World Neurosurg. 2024 Jan 1; 181: 125136125-136.

AbstractThe burden of disease regarding lumbar and cervical spine pain is a long-standing, pervasive problem within medicine that has yet to be resolved. Specifically, neck and back pain are associated with chronic pain, disability, and exorbitant health care use worldwide, which have only been exacerbated by the increase in overall life years and chronic disease. Traditionally, patients with significant pain and disability secondary to disease of either the cervical or lumbar spine are treated via fusion or discectomy. Although these interventions have proved curative in the short-term, numerous longitudinal studies evaluating the efficacy of traditional management have reported severe impairment of normal spinal range of motion, as well as postoperative complications, including neurologic injury, radiculopathy, osteolysis, subsidence, and infection, paired with less than desirable reoperation rates. Consequently, there is a call for innovation and improvement in the treatment of lumbar and cervical spine pain, which may be answered by a modern technique known as intervertebral disc arthroplasty, or total disc replacement (TDR). Thus, this review aims to describe the management strategy of TDR and to explore updated considerations for its use in practice, both to help guide clinical decision making.Copyright © 2023 Elsevier Inc. All rights reserved.

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