• Rei Hirose, Yuya Tsurutani, Takero Nakatsue, Akane Hirataka, Kazuki Nakai, and Jun Saito.
• Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Japan.
• Intern. Med. 2024 May 15; 63 (10): 140514131405-1413.

AbstractA 26-year-old woman experienced sudden loss of consciousness with respiratory arrest while engaged in a heated conversation shortly after consuming a carbohydrate-rich meal; she was resuscitated immediately. Severe hypokalemia became evident and was deemed to have caused lethal arrhythmia. She was diagnosed with a left aldosterone-producing adenoma and achieved remission following partial adrenalectomy. Primary aldosteronism is frequently complicated by hypokalemia; however, hypokalemia-induced lethal arrhythmias are rare. Clinicians should recognize that primary aldosteronism can potentially cause sudden death in apparently healthy individuals; hence, an early diagnosis and proper treatment are critical.

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