• Respir Care Clin N Am · Sep 2004

    Review

    What is the role of high-frequency ventilation in adult respiratory distress syndrome?

    • Raquel R Bartz.
    • Division of Pulmonary, Allergy, and Critical Care and the Department of Anesthesia, Duke University Medical Center, Box 3221, Durham, NC 27710, USA. bartz001@mc.duke.edu
    • Respir Care Clin N Am. 2004 Sep 1;10(3):329-39, vi.

    AbstractThe goal of positive-pressure mechanical ventilation is to provide respiratory support to a patient while allowing the underlying diseased lungs to heal. Research using both animal models and humans suggests that positive-pressure ventilation can injure the lung through both overdistension and under recruitment. Theoretically,the ultimate lung-protective strategy would consist of very small tidal volumes to avoid pressure swings while maintaining alveolar recruitment. High-frequency ventilation provides such a strategy of mechanical ventilation. This article examines the utility of using high-frequency modes of mechanical ventilation in supporting the patient with ARDS.

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