• Miguel Ángel Fernández-Barrera, Edith Lara-Carrillo, Rogelio José Scougall-Vilchis, América Patricia Pontigo-Loyola, Leticia Ávila-Burgos, Juan Fernando Casanova-Rosado, Alejandro José Casanova-Rosado, Mirna Minaya-Sánchez, and Carlo Eduardo Medina-Solís.
• Program of Doctorate in Health Sciences, Autonomous University State of Mexico, Toluca.
• Medicine (Baltimore). 2019 Jul 1; 98 (30): e16634e16634.

IntroductionDental caries is the most frequent oral disease worldwide and the main cause of tooth loss in children and young adults. One of the most frequently affected areas is the occlusal surfaces of the first permanent molars (FPM) due to their morphological complexity. At present, several preventive treatments can reduce the incidence of this disease in school populations. In Mexico, the most commonly used technologies are those derived from some presentation of fluoride; on the other hand, research on this topic has been limited.ObjectiveTo determine the cost-effectiveness of two different methods for preventing the incidence of caries on the FPM of schoolchildren (6-8 years of age) from public primary schools.Material And MethodsThis is a randomized experimental design. Participants will be assigned to two treatment groups of 114 each. In the first group, pit and fissure sealants will be applied, whereas the second group will receive a fluoride varnish. The work will be carried out in schoolchildren that attend public elementary schools in the state of Hidalgo, Mexico. The result variable will be the incidence of caries and the total cost of each of the interventions will be calculated in order to calculate the intervention's cost-effectiveness.ConclusionThis work will allow us to compare the cost-effectiveness of the pit and fissure sealants and the fluoride varnish in order to determine which offers the best results.

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