• Internal medicine · Jun 2024

    Case Reports

    Post-allogeneic Hematopoietic Stem Cell Transplantation Portal Hypertension Not Associated with Liver Cirrhosis, Veno-occlusive Disease, or Graft-versus-host Disease: A Case Report.

    • Masaki Miyazawa, Masahiro Yanagi, Tomoyoshi Chiba, Hidenori Kido, Toshiki Matsuo, Masaki Nishitani, Noriaki Orita, Noboru Takata, Tomoyuki Hayashi, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Takeshi Terashima, Noriho Iida, Shinya Yamada, Hajime Takatori, Tetsuro Shimakami, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, and Taro Yamashita.
    • Department of Gastroenterology, Kanazawa University Hospital, Japan.
    • Intern. Med. 2024 Jun 1; 63 (11): 156315681563-1568.

    AbstractWe herein report a rare case of idiopathic portal hypertension (IPH)-like disease that developed after allogeneic hematopoietic stem cell transplantation (allo-HSCT). A 53-year-old woman who underwent allo-HSCT for acute myeloid leukemia showed portal hypertension with radiological and histopathological findings consistent with IPH, distinct from veno-occlusive disease (VOD) and graft-versus-host disease (GVHD) of the liver. This case highlights the importance of considering IPH-like disease as a potential cause of portal hypertension after allo-HSCT. Awareness of this complication can aid in the early diagnosis and appropriate management of patients post allo-HSCT.

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