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- Mari Kitahara, Masahiko Sumi, Hiroko Kazumoto, Tsutomu Shishido, Toshimitsu Ueki, Yuki Hiroshima, Katsuhiko Kamei, and Hikaru Kobayashi.
- Department of Hematology, Nagano Red Cross Hospital, Japan.
- Intern. Med. 2024 May 15; 63 (10): 146514711465-1471.
AbstractScedosporium/Lomentospora infections are rare and are associated with a high mortality rate in immunocompromised patients. A 69-year-old man with nontuberculous mycobacteria (NTM) died during induction chemotherapy for acute myeloid leukemia because of multiple organ failure due to pneumonia. During an autopsy, Lomentospora prolificans was detected using a fungal gene analysis of the blood, lungs, spleen, kidneys, and intestines, and Scedosporium aurantiacum was detected in the lungs. NTM disease may predispose patients to Scedosporium/Lomentospora infections. Physicians should consider Scedosporium/Lomentospora spp. as an invasive fungal infection that occurs during myelosuppression, particularly when NTM is a complication.
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