• Curr Opin Anaesthesiol · Feb 2024

    Review

    Acute kidney injury after cardiac surgery.

    • Thilo von Groote, Mahan Sadjadi, and Alexander Zarbock.
    • Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
    • Curr Opin Anaesthesiol. 2024 Feb 1; 37 (1): 354135-41.

    Purpose Of ReviewPatients undergoing cardiac surgery are at high risk to develop cardiac surgery-associated acute kidney injury (CS-AKI) postoperatively. CS-AKI is associated with an increased risk for persistent renal dysfunction, morbidity and mortality. This review summarizes the epidemiology and pathophysiology of CS-AKI, as well as current treatment and prevention strategies.Recent FindingsAs AKI is a syndrome with complex pathophysiology, no causative treatment strategies exist. Recent advances in the field of AKI biomarkers offer new perspectives on the issue and the implementation of biomarker-guided preventive strategies may reduce rates of CS-AKI. Finally, nephroprotective treatments and angiotensin II as a novel vasopressor may offer new opportunities for high-risk patients undergoing cardiac surgery.SummaryBased on the described novel approaches for early detection, prevention and management of CS-AKI, a precision-medicine approach should be implemented in order to prevent the development of AKI in patients undergoing cardiac surgery.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

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