• Rawn Salenger, Sameer Hirji, Amanda Rea, Busra Cangut, Vicki Morton-Bailey, Alexander J Gregory, Rakesh C Arora, Michael C Grant, Jacob Raphael, Daniel T Engelman, and ERAS Cardiac Working Group.
• Department of Surgery, University of Maryland School of Medicine, Baltimore, Md. Electronic address: rawnsalenger@umm.edu.
• J. Thorac. Cardiovasc. Surg. 2024 Sep 1; 168 (3): 890897.e4890-897.e4.

ObjectivesThere are multiple published guidelines on comprehensive patient blood management (PBM), centered on the 3 pillars of PBM: managing preoperative anemia, minimizing blood loss, and tolerating intraoperative/postoperative anemia. We sought to create an order set to facilitate widespread implementation of evidence-based PBM for cardiac surgery patients.MethodsSubject matter experts were consulted to translate existing guidelines and literature into a sample turnkey order set (TKO) for PBM. Orders derived from consistent class I, class IIA, or equivalent recommendations across referenced guidelines and consensus manuscripts appear in the TKO in bold type. Selected orders that were inconsistently class I or IIA, class IIB, or supported by published evidence are presented in italic type.ResultsPreoperatively, there are strong recommendations to screen and treat preoperative anemia with iron replacement and erythropoietin and to discontinue dual antiplatelet therapy if the patient can safely wait for surgery. Intraoperative orders outline the routine use of an antifibrinolytic agent, cell saver, point of care viscoelastic testing, and use of a standard transfusion algorithm. The order set also reflects strong recommendations intraoperatively and postoperatively for agreed-upon hemoglobin thresholds to consider transfusion of packed red blood cells. A hemoglobin threshold should be adopted according to local team consensus and should trigger a discussion regarding transfusion.ConclusionsThe benefit of a multidisciplinary PBM care pathway in cardiac surgery has been well established, yet implementation remains variable. Using recommendations from existing guidelines, we have created a TKO to facilitate the implementation of PBM.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

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