• Internal medicine · Jun 2024

    Case Reports

    Disappearance of Hepatocellular Adenoma in a Patient with Cornelia de Lange Syndrome after Treatment with Transcatheter Arterial Embolization.

    • Kazuhide Takata, Takanori Kitaguchi, Hiroaki Tokushige, Takahiro Nagata, Takashi Miyayama, Kumiko Shibata, Hiromi Fukuda, Ryo Yamauchi, Atsushi Fukunaga, Takashi Tanaka, Keiji Yokoyama, Satoshi Shakado, Kengo Yoshimitsu, Hironori Kusano, Shotaro Sakisaka, and Fumihito Hirai.
    • Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine, Japan.
    • Intern. Med. 2024 Jun 1; 63 (11): 156915731569-1573.

    AbstractCornelia de Lange syndrome (CdLS) is a congenital disorder occasionally associated with congenital portosystemic shunt (CPSS). We herein report a patient with CdLS and CPSS who developed hepatocellular adenomas (HCAs). The patient presented to our hospital for the further investigation of newly diagnosed liver tumors. Imaging findings and pathological examination results indicated that the liver tumors were inflammatory HCAs that subsequently shrank following transcatheter arterial embolization (TAE). Patients with CdLS and CPSS are at risk of developing HCAs, and TAE may be an effective management strategy for HCA in these patients.

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