• Internal medicine · Jun 2024

    Case Reports

    Clostridium paraputrificum Bacteremia in a Patient with Rectal Cancer after Receiving Antibiotic Therapy for Acute Pharyngolaryngitis.

    • Yasunori Maeda, Ryo Miura, Takuma Echizenya, Kentaro Hoshi, Norihito Kubo, Hajime Nakai, Kazuhito Matsumoto, Shin Ikejima, Naomi Kudo, and Atsushi Matsubara.
    • Department of Otorhinolaryngology, Odate Municipal General Hospital, Japan.
    • Intern. Med. 2024 Jun 1; 63 (11): 165316571653-1657.

    AbstractClostridium paraputrificum bacteremia is very rare, and its clinical importance is poorly understood. An 86-year-old man was receiving lascufloxacin therapy for acute pharyngolaryngitis before presenting to our emergency department with a recurrent fever. Two sets of blood cultures on admission revealed C. paraputrificum. A stool culture showed a reduced presence of intestinal commensal bacteria. After admission, the patient's fever resolved without antibiotics. Colonoscopy revealed a rectal tumor. Rectal tumor and microbial substitutions caused by antibiotics may have led to bacteremia. When treating C. paraputrificum bacteremia, physicians should be mindful of coexisting gastrointestinal disorders and a history of antibiotic administration.

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