• World Neurosurg · Jan 2024

    Case Reports

    Expansive spinal cord injury after autologous olfactory mucosal transplantation: case report and systematic review.

    • Bastos Siqueira SoaresTitoTDepartment of Medicine, Ceará State University, Fortaleza, Ceará, Brazil. Electronic address: titobastos.med@gmail.com., da Silva Damasceno GomesJosé ÍtaloJÍDepartment of Medicine, Ceará State University, Fortaleza, Ceará, Brazil., Gomes Barros MaiaAmandaADepartment of Medicine, Ceará State University, Fortaleza, Ceará, Brazil., Pimentel GuimarãesIngredIDepartment of Medicine, Ceará State University, Fortaleza, Ceará, Brazil., Késia Sindy Alves Ferreira Pereira, Vinicius Chagas de Morais Moreira, Alves Sobreira NetoAntônioADepartment of Medicine, Ceará State University, Fortaleza, Ceará, Brazil., Leonardo Jose Monteiro de Macedo Filho, Gilnard Caminha de Menezes Aguiar, and Alverne Freitas de AlbuquerqueLucasLDepartment of Neurosurgery, Dr. José Frota Institute, Fortaleza, Ceará, Brazil; Department of Neurosurgery, General Hospital of Fortaleza, Fortaleza, Ceará, Brazil..
    • Department of Medicine, Ceará State University, Fortaleza, Ceará, Brazil. Electronic address: titobastos.med@gmail.com.
    • World Neurosurg. 2024 Jan 1; 181: e551e561e551-e561.

    ObjectiveTo present strategies for managing tumor mass formation and their corresponding postoperative outcomes.MethodsWe conducted a systematic literature review following the guidelines and protocol of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We searched the PubMed and EMBASE databases, screened titles and abstracts, and further evaluated full-text publications to select relevant studies. Additionally, a narrative review of other pertinent articles on PubMed was performed. Case reports, cohort studies, and clinical trials were included. Animal studies were excluded.ResultsOf 6 patients enrolled in this study, most had American Spinal Injury Association Impairment Scale grade A (66.7%) following intramedullary injury, and 1 patient had American Spinal Injury Association Impairment Scale grade D (16.65%). The discovery time of the intramedullary mass formation ranged from approximately 5 to 14 years. Surgical intervention was performed in most cases (66.7%), with improvement reported in 3 of the surgical cases (75%). The majority of cases (83.3%) involved cervical lesions, while only 1 case (16.7%) involved a thoracic lesion.ConclusionsDue to the scarcity of described cases, there is no specific treatment for this tumor. Although our patient remained stable after conservative treatment, other studies have shown improvement in symptoms after mass resection. It is essential that the management of this complication be researched further due to the variety of clinical characteristics presented.Copyright © 2023 Elsevier Inc. All rights reserved.

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