• Juan Carlos Prieto, Víctor Rossel, Ricardo Larrea, Alberto Barría, Juan Carlos Venegas, Fernando Verdugo, Marcelo Potthoff, Carlos Gidi, Alex Villablanca, Iván Criollo, Viviana Noriega, Francisco Cumsille, Marcelo Llancaqueo, and Fernando Lanas.
• Departamento Cardiovascular, Hospital Clínico, Universidad de Chile, Santiago, Chile.
• Rev Med Chil. 2022 Jun 1; 150 (6): 711719711-719.

BackgroundPatients with a cardiovascular (CV) history may be at greater risk of becoming ill and die due to SARS-CoV-2.AimTo assess the incidence of CV complications in COVID-19 patients, the type of complication, and their association with CV history.Material And MethodsThe clinical course of 1,314 patients with COVID-19 admitted consecutively to critical care units of 10 Chilean hospitals was registered between April and August of 2020.ResultsThe median age of patients was 59 years and 66% were men. One hundred-four (8%) had a CV history, namely heart failure (HF) in 53 (4.1%), coronary heart disease in 50 (3.8 %), and atrial fibrillation in 36 (2.7 %). There were CV complications in 359 patients (27.3%). The most common were venous thrombosis in 10.7% and arrhythmias in 10.5%, HF in 7.2%, type 2 acute myocardial infarction in 4.2%, arterial thrombosis in 2.0% and acute coronary syndrome (ACS) in 1.6%. When adjusted by age, sex and risk factors, only HF (Odds ratio (OR) = 7.16; 95% confidence intervals (CI), 3.96-12.92) and ACS (OR = 5.44; 95% CI, 1.50-19.82) were significantly associated with CV history. There was no association with arrhythmias, type 2 acute myocardial infarction, arterial or venous thrombosis.ConclusionsPatients with a history of CV disease are at greater risk of suffering HF and ACS when hospitalized due to COVID-19. Arrhythmias, type 2 AMI, and arterial or venous thrombosis occur with the same frequency in patients with or without CV history, suggesting that these complications depend on inflammatory phenomena related to the infection.

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