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Case Reports
Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency.
- José Luis Cabrerizo-García, Mariano Sebastián-Royo, Nerea Montes, and Begoña Zalba-Etayo.
- Internal Medicine Service, Defense General Hospital, Zaragoza, Spain. j_cabrerizo@hotmail.com
- Sao Paulo Med J. 2012 Jan 1; 130 (4): 259262259-62.
ContextDecreased vitamin B12 concentration does not usually result in clinical or hematological abnormalities. Subacute combined spinal cord degeneration and pancytopenia are two serious and rarely displayed consequences that appear in severe deficits.Case ReportWe present the case of a patient with subacute combined spinal cord degeneration and pancytopenia secondary to severe and sustained vitamin B12 deficiency. Such cases are rare nowadays and have potentially fatal consequences.ConclusionsVitamin B12 deficiency should be taken into consideration in the differential diagnosis in cases of blood disorders or severe neurological symptoms. Early diagnosis and treatment can avoid irreversible consequences.
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