• Crit Care · Jan 2004

    Review Comparative Study

    To filter blood or universal leukoreduction: what is the answer?

    • Marc J Shapiro.
    • SUNY-Stony Brook School of Medicine, General Surgery, New York, USA. mjshapiro@notes.cc.sunysb.edu
    • Crit Care. 2004 Jan 1; 8 Suppl 2: S27S30S27-30.

    AbstractThe safety of the blood supply has been a concern over the past 20-30 years because of the transmission of infectious diseases. Blood is still routinely tested for viruses, and leukoreduction is an effective strategy to reduce the transmission of cell-associated viruses. Clinically, the benefits of leukoreduction include decreases in transfusion reactions, HLA alloimmunization, infections, fever episodes, and antibiotic use. Although leukoreduction will add cost to a unit of blood, projections indicate that leukoreduced blood will become the standard of care.

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