-
Observational Study
[Fine-tuning of antithrombotic therapy in patients with non-valvular atrial fibrillation. The AFINVA register].
- Daniela Dubois Marques, Vicente Mora Llabata, Julián Pacheco Arroyo, Salvador Gasull Insertis, Manuela Vicente Cañizares, Ildefonso Roldán Torres, and En representación de los investigadores del Registro AFINVA.
- Servicio de Cardiología, Hospital Universitario Dr Peset, Valencia, España.
- Aten Primaria. 2018 Jun 1; 50 (6): 340349340-349.
ObjectiveTo determine whether antithrombotic treatment (ATT) in patients with non-valvular atrial fibrillation in a health area complies with the recommendations of current clinical guidelines.DesignProspective observational study.LocationPrimary Health Care Centres and Cardiology Department of a Health Department of the Valencian Community, Spain.ParticipantsA total of 505 patients with nonvalvular atrial fibrillation were included in the study.Main MeasurementsATT was deemed to be inappropriate in patients with a CHA2DS2-VASc score ≥1 and who were not under oral anticoagulation, in patients treated with antivitaminK drugs, and poor control of oral anticoagulation, or with antiplatelet therapy inappropriately associated with anticoagulation, and in patients on ATT with a CHA2DS2-VASc score=0.ResultsThe median age was 77.4±10years. The ATT was considered inadequate in 58% of cases. Factors independently associated with inadequate ATT were age (OR: 1.02 [1-1.04]; P=.029), hypothyroidism (OR: 1.98 [1.14-3.43]; P=.015), ischaemic heart disease (OR: 1.3 [1.15-2.59]; P=.008) and paroxysmal non-valvular AF (OR: 2.11 [1.41-3.17]; P<.0001).ConclusionsThese data underline the high prevalence of inadequate ATT in daily practice, as well its different causes.Copyright © 2017 Elsevier España, S.L.U. All rights reserved.
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