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Comment Randomized Controlled Trial
In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge.
- KoKo Aung and Thwe Htay.
- Paul L. Foster School of Medicine, El Paso, Texas, USA (T.H.).
- Ann. Intern. Med. 2023 Nov 1; 176 (11): JC127JC127.
AbstractCopaescu AM, Vogrin S, James F, et al. Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial. JAMA Intern Med. 2023;183:944-952. 37459086.
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