• Medicina clinica · Jan 2024

    Red flags of cardiac amyloidosis in patients with spinal stenosis and yellow ligament hypertrophy.

    • Martín Negreira Caamaño, Marco Aurelio Ramírez Huaranga, Ana María García Vicente, Miguel Ángel Rienda Moreno, David Castro Corredor, and Jesús Piqueras Flores.
    • Servicio de Cardiología, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
    • Med Clin (Barc). 2024 Jan 26; 162 (2): 606360-63.

    IntroductionStudies addressing the prevalence of cardiac amyloidosis (CA) among patients with spinal stenosis (SS) are lacking. The identification of the red flags (RF) of CA could lead to early detection of cases of CA. The primary objective of this study was to address the prevalence of RF of CA among patients with SS.MethodsTransversal study including consecutive cases with SS and yellow ligament hypertrophy (YLH). A clinical assessment that included electrocardiogram, echocardiogram and urine and blood test was performed. A clinical suspicion of CA was defined by the presence of left ventricular hypertrophy plus any RF.ResultsOne hundred and three patients with SS and YLH were assessed. The prevalence of RF was high: heart failure: 18.4%; aortic stenosis: 1.9%; carpal tunnel syndrome: 7.8%; bicipital tendon rupture: 1.9%; arterial hypotension: 17.4%; polyneuropathy symptoms: 51.5%; pseudoinfarction pattern: 3.9%; low voltages: 15.5%; conduction abnormalities: 15.5%; decreased longitudinal strain: 25.3%; apical sparing pattern: 3.9%. The 57.3% of the cohort met the CA suspicion criteria.ConclusionThe prevalence of RF of CA is high among patients with SS and YLH. A high proportion of patients met the CA suspicion criteria.Copyright © 2023 Elsevier España, S.L.U. All rights reserved.

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