• Paediatric anaesthesia · Mar 2010

    Dexmedetomidine: perioperative applications in children.

    • Vivian Man Ying Yuen.
    • Department of Anaesthesiology, Queen Mary Hospital, Pokfulam, Hong Kong, China. vtang131@hku.hk
    • Paediatr Anaesth. 2010 Mar 1;20(3):256-64.

    AbstractDexmedetomidine is a highly specific and selective alpha-2-adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be explored. In this review, various uses of dexmedetomidine are discussed in detail.

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