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- Gunar Günther.
- Division of Clinical Infectious Diseases, Medical Clinic, Research Center Borstel, Borstel, Germany, and Department of Medicine, University of Namibia School of Medicine, Windhoek, Namibia gguenther@fz-borstel.de.
- Clin Med. 2014 Jun 1; 14 (3): 279285279-85.
AbstractMultidrug-resistant and extensively drug-resistant tuberculosis are recent global health issues, which makes tuberculosis - after the success of short course treatment during the second half of the last century - a major health challenge. Globalisation, health inequalities, competing economic interests and political instability contribute substantially to the spread of drug-resistant strains, which are associated with high rates of morbidity and mortality. Issues such as increasing transmission of drug-resistant strains, poor diagnostic coverage and a lengthy, toxic treatment need to be overcome by innovative approaches to tuberculosis control, prevention, diagnostics and treatment. This review addresses recent developments and future concepts.© 2014 Royal College of Physicians.
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