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- Omar Hamam, Samuel C Cartmell, and Javier M Romero.
- Neurovascular Laboratory R.H Ackerman, Radiology, Mass General Brigham, 55 Fruit street, Boston, MA, 02115, USA.
- Neuroimaging Clin. N. Am. 2024 Feb 1; 34 (1): 677967-79.
AbstractSmall artery vasculitis of the CNS is a rare and serious condition characterized by the inflammation of blood vessels within the brain and spinal cord. There are two groups of small artery vasculitis determined by the presence or absence of immunoglobulin complex deposition in the vessel wall. The former includes anti-glomerular basement membrane disease, cryoglobulinemic vasculitis, and IgA vasculitis. Absence of immune complex deposition is associated with anti-neutrophil cytoplasmic antibody (ANCA) and includes microscopic polyangiitis, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis, and primary angiitis of the CNS. These conditions present a diagnostic challenge in which imaging plays a crucial role.Copyright © 2023 Elsevier Inc. All rights reserved.
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