• Ann. Intern. Med. · Dec 2023

    Editorial Comment

    Rebound of COVID-19 With Nirmatrelvir-Ritonavir Antiviral Therapy.

    • Myron S Cohen and Elizabeth R Brown.
    • Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
    • Ann. Intern. Med. 2023 Dec 1; 176 (12): 167216731672-1673.

    AbstractIn their article, Edelstein and colleagues provide the results of an observational study of virologic response in patients who received treatment with nirmatrelvir–ritonavir (N-R) versus those who received no COVID-19 therapy. The editorialists discuss the findings and emphasize the need for further consideration of the dosage, timing, and duration of treatment to inform optimal use of N-R.

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