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- Kazuhiro Yokota, Kota Morimoto, Hiroaki Yazawa, Takuma Tsuzuki Wada, Tomoyuki Sakamoto, Yasuhito Terui, Satoru Kaneko, Tsutomu Inoue, Hirokazu Okada, Yuji Akiyama, and Toshihide Mimura.
- Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan.
- Intern. Med. 2024 Jun 1; 63 (11): 164516521645-1652.
AbstractWe herein report a case of diffuse large B-cell lymphoma (DLBCL) involving multiple renal and bone infiltrations presenting with giant cell arteritis (GCA)-like manifestations. One month prior, the present patient had left-sided temporal headache, jaw claudication, and renal failure. The patient was diagnosed with DLBCL based on a renal biopsy. After rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone plus intrathecal methotrexate/cytarabine/prednisone and rituximab, high-dose methotrexate, and cytarabine chemotherapy, the patient's clinical manifestations improved, and complete remission was achieved. DLBCL rarely but occasionally presents with GCA-like manifestations or multiple renal and bone infiltrations, highlighting the need for prompt and aggressive combination chemotherapy.
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