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Int J Gynaecol Obstet · Oct 2011
Practice GuidelineThe combination of mifepristone and misoprostol for the termination of pregnancy.
- Anibal Faúndes, FIGO Working Group on Prevention of Unsafe Abortion and its Consequences, and International Federation of Gynecology and Obstetrics.
- Int J Gynaecol Obstet. 2011 Oct 1;115(1):1-4.
AbstractThe combination of 200mg of mifepristone followed by 25 μg to 800 μg (depending on gestational age) of misoprostol has been shown to be effective for the termination of pregnancy throughout gestation. The dose of misoprostol should be reduced as gestational age increases. Mifepristone is not indicated for induction of labor with a live fetus because there are no data to confirm that it does not have a possible deleterious fetal effect. The course of treatment and prerequisites for medical abortion and recommended mifepristone and misoprostol regimens for different gestational ages are described, along with the side effects, management of complications, and postabortion care. The use of the mifepristone-misoprostol combination regimen for induction of labor in cases of fetal death is also described.Copyright © 2011 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
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