• Yiu-Tai Li, James Ching-Hung Hsieh, Guang-Qiong Hou, Tien-Hui Chen, Yi-Chih Chu, Ta-Chin Lin, Long-Ching Kuan, Mau Lin, Hsun-Han Tang, and Tsung-Cheng Kuo.
• Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan.
• Taiwan J Obstet Gynecol. 2011 Mar 1;50(1):11-4.

ObjectiveSimultaneous mifepristone 200mg and vaginal misoprostol 800μg produces a complete abortion rate of approximately 90% at up to 63 days of gestation. The aim of this study was to determine the effectiveness of concurrent administration of mifepristone 200mg and vaginal misoprostol 600μg with respect to early medical abortion.Materials And MethodsA total of 254 women with undesired pregnancies of less than 49 days of gestation were enrolled. All women received oral mifepristone 200mg and vaginal misoprostol 600μg concurrently. Follow-up assessment by transvaginal ultrasonography was performed 3 days and 2 weeks after treatment.ResultsEfficacy outcome was analyzed for 242 women (95.3%) after excluding 12 individuals lost to follow-up. The complete abortion rate was 92.6%. The mean induction to abortion interval was about 5.8hours. The mean bleeding duration was about 12.6 days. The women indicated that the side effects were tolerable and 90% of them said that their experience was satisfactory.ConclusionConcurrent administration of oral mifepristone 200mg and vaginal misoprostol 600μg is an efficacious regimen for medical abortion of pregnancies up to 49 days of gestation.Copyright © 2011. Published by Elsevier B.V.

28 keywords...

hide…