• Nihal Gurlek Celik, Ahmet Kagan Karabulut, Zeliha Fazliogullari, Haluk Gumus, Hakan Cebeci, and DoganNadire UnverNU0000-0001-5696-5547Selçuk University, School of Medicine, Department of Anatomy - Konya, Turkey..
• Amasya University, Faculty of Medicine, Department of Anatomy - Amasya, Turkey.
• Rev Assoc Med Bras (1992). 2023 Jan 1; 69 (12): e20230949e20230949.

ObjectiveMultiple sclerosis is an autoimmune disease that commonly affects the cervical part of the spinal cord. The aim of this study was to evaluate the relationship between cervical spinal cord atrophy and clinical disability in multiple sclerosis patients.MethodsWe examined the cervical spinal cord area measurements of 64 multiple sclerosis patients and 64 healthy control groups over the images obtained by a T2-weighted magnetic resonance imaging device.ResultsThe C2-3, C3-4, C4-5, and C6-7 axial cross-sectional surface area values of the patient group were statistically lower than those of the control group (p<0.05). A negative correlation was found between patients' Expanded Disability Status Scale scores and C4-5, C5-6, and C6-7 axial area (axial area p<0.05; r1=-0.472, r2=-0.513, and r3=-0.415).ConclusionWhen all parameters were evaluated, the data of our control group were found to be higher than the multiple sclerosis groups. There appears to be a significant relationship between patients with cervical spinal cord atrophy and an increase in Expanded Disability Status Scale scores.

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