• Internal medicine · Jul 2024

    Case Reports

    Successful Treatment of Primary Mediastinal Large B-cell Lymphoma with DA-EPOCH-Rituximab Therapy in a Transgender Woman.

    • Sanshiro Nakao, Sho Tanaka, Kazuki Abe, Tomomi Komiyama, Yoshiya Sugiura, Chiaki Nakaseko, and Naomi Shimizu.
    • Department of Hematology, Toho University Sakura Medical Center, Japan.
    • Intern. Med. 2024 Jul 1; 63 (13): 192319271923-1927.

    AbstractIn recent years, lesbian, gay, bisexual, and transgender (LGBT) populations have been gaining acceptance in society. However, very few cases of malignancy in the LGBT population have been reported thus far. We herein report a transgender woman receiving estrogen supplementation who developed primary mediastinal large B-cell lymphoma (PMBCL) and was treated with dose-adjusted EPOCH-rituximab (DA-EPOCH-R) therapy. The patient achieved complete remission after the sixth course of DA-EPOCH-R therapy. To help this LGBT patient continue receiving chemotherapy smoothly on admission, adjusting the hospital environment, such as the allocation of rooms, was essential.

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