• Medicina clinica · Jan 2024

    Risk factors associated with osteomyelitis due to Corynebacterium striatum in patients with diabetic foot.

    • María Del Mar Bermejo Olano, Carolina Campelo Gutierrez, Rafael Hervas Gómez, Jesús Manuel Alfayate García, Juan Pedro Sánchez Ríos, and Leonor Moreno Núñez.
    • Servicio de Medicina Interna, Hospital Universitario Fundación Alcorcón, Madrid, España.
    • Med Clin (Barc). 2024 Jan 12; 162 (1): 151815-18.

    ObjectiveCorynebacterium striatum (CS) is an emerging micro-organism in diabetic foot infection for which there are currently few studies. The objective was to analyze the risk factors (RF) related to CS osteomyelitis in patients with diabetic foot.MethodsA case-control study was conducted in the Diabetic Foot Unit between 2015 and 2021. Forty-four patients with osteomyelitis due to CS (cases) and 44 patients with osteomyelitis due a different micro-organism (controls) were included.ResultsPeripheral artery disease (OR: 2.8, p = 0.037), atrial fibrillation (OR: 3.7, p = 0.034), ischemic diabetic foot (OR: 3.3, p = 0.020) and previous prolonged antibiotic therapy more than 14 days (OR: 3.4, p = 0.012) were identified as RF for osteomyelitis due to CS. When performing the multivariate analysis antibiotic therapy >14 days was independent RF (OR: 3.46; p = 0.017).ConclusionsPrevious antibiotic therapy received more than 14 days is an independent and statistically significant RF for CS osteomyelitis in patients with diabetic foot.Copyright © 2023 Elsevier España, S.L.U. All rights reserved.

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