• Cochrane Db Syst Rev · Jan 2009

    Review

    WITHDRAWN: Bioresorbable fixation devices for musculoskeletal injuries in adults.

    • Jayant S Jainandunsing, Maarten van der Elst, and Christian van der Werken.
    • Surgical ICU, University Medical Centre Groningen, Hanzeplein 1, PO Box 30 001, Groningen, Groningen, Netherlands, 9700 RB. jsjainandunsing@yahoo.com
    • Cochrane Db Syst Rev. 2009 Jan 21; 2009 (1): CD004324CD004324.

    BackgroundBioresorbable implants for musculoskeletal injuries involving bone and ligaments in adults might have significant advantages compared to the conventionally used non-resorbable metal implants because they lead to a gradual transfer of the mechanical load from the implant to the healing bone and do not require a secondary removal operation. Tissue reactions may present a problem and bioresorbable screws are mechanically not as strong as their metal counterparts.ObjectivesTo compare bioresorbable implants to non-resorbable implants with respect to functional outcome, wound infections, other complications and reoperation rate,in the fixation of bone fractures or re-attachment of soft tissue to bone.Search StrategyWe searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (March 2004), the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 1, 2004), MEDLINE (1966 to February 2004), EMBASE (1988 to February 2004), BL Inside (to February 2004), SIGLE (to February 2004), the metaRegister of Controlled Trials at http//:controlled-trials.com/, and reference lists of articles.Selection CriteriaRandomised controlled trials (RCTs) and quasi-randomised trials, comparing bioresorbable osteosynthesis with metal osteosynthesis (including titanium and stainless steel implants) were included.Data Collection And AnalysisReview authors independently assessed trial quality and extracted data. Data were pooled where relevant and possible. Sub-analyses for specific type of fractures and for specific type of tissue reactions were performed. Requests for more information were sent to trialists.Main ResultsNo significant difference between the bioresorbable and other implants could be demonstrated with respect to functional outcome, infections and other complications. Reoperation rates were lower in some of the groups of people treated with bioresorbable implants.Authors' ConclusionsIn a selected group of compliant patients with simple fractures, the use of bioresorbable fixation devices might be advantageous.

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